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Side-Effects of Semaglutide Serious side-effects include: Allergic reactionsskin rash, itching, hives, swelling of the face, lips, tongue, or throat Change in vision Dehydrationincreased thirst, dry mouth, feeling faint or lightheaded, headache, dark yellow or brown urine Gallbladder problemssevere stomach pain, nausea, vomiting, fever Heart palpitationsrapid, pounding, or irregular heartbeat Kidney injurydecrease in the amount of urine, swelling of the ankles, hands, or feet Pancreatitissevere stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting Thoughts of suicide or self-harm, worsening mood, feelings of depression Thyroid cancernew mass or lump in the neck, pain or trouble swallowing, trouble breathing, hoarseness Common and less serious side effects are: Diarrhea Loss of appetite Nausea Stomach pain Vomiting Cost of Semaglutide The cost of semaglutide can range from $968.52 to 1,349.02 per month

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In the UK, NICE guidance specifies that these medications should only be prescribed within specialist weight management services and for people meeting specific BMI thresholds (typically BMI 35 kg/m with weight-related comorbidities or 40 kg/m without), alongside diet and physical activity interventions